"The Global Gene Synthesis Market was valued at USD 4.73 billion in 2025 and is projected to reach USD 18.95 billion by 2034, growing at a CAGR of 16.68%."
The Gene Synthesis Market is witnessing robust growth driven by the expanding applications of synthetic biology, increased funding in genomics research, and advancements in DNA synthesis technologies. Gene synthesis refers to the artificial construction of genes in a laboratory setting, enabling researchers to design and assemble sequences tailored for specific biological functions. It plays a critical role in fields such as drug discovery, vaccine development, agricultural biotechnology, and personalized medicine. Companies are leveraging gene synthesis to develop novel biologics, engineer metabolic pathways, and conduct functional genomics studies. The demand for high-throughput and error-free synthetic genes has fostered innovations in automated platforms, chip-based synthesis, and enzymatic DNA assembly methods.
Market expansion is also being catalyzed by the growing interest in CRISPR genome editing, synthetic vaccines, and the development of cell and gene therapies. Organizations across pharmaceuticals, academic research, and contract research organizations are increasingly adopting synthetic genes to accelerate R&D pipelines and optimize production workflows. Additionally, supportive government initiatives and the declining cost of synthesis per base pair are making gene synthesis more accessible. North America leads the market due to its established research infrastructure, while Asia Pacific is emerging rapidly with investments in biotech innovation. The gene synthesis market is poised to remain a fundamental pillar of modern life sciences innovation.
Gene Synthesis Market in North AmericaNorth America dominates the Gene Synthesis Market due to its mature biotechnology infrastructure, advanced genomic research capabilities, and robust presence of pharmaceutical and biopharmaceutical companies. The U.S. is the leading contributor, backed by continuous funding for genetic engineering, CRISPR gene editing, and synthetic biology. The region’s academic institutions and private firms are driving innovation in DNA synthesis automation, enabling cost and time efficiencies. With increasing applications in diagnostics, personalized medicine, and vaccine development, the region offers numerous growth opportunities for companies investing in precision gene synthesis technologies.
Gene Synthesis Market in Asia PacificThe Asia Pacific Gene Synthesis Market is expanding rapidly, fueled by growing investments in biotechnology, favorable government policies, and the presence of skilled labor and low-cost manufacturing. Countries such as China, India, Japan, and South Korea are leading the charge, with substantial developments in clinical research, agricultural biotechnology, and pharmaceutical production. Rising collaborations between global players and regional research institutes are accelerating technology transfer and expanding the scope of synthetic gene applications across healthcare and industrial biotechnology sectors.
Gene Synthesis Market in EuropeEurope’s Gene Synthesis Market benefits from strong regulatory frameworks, significant investments in R&D, and cross-border academic and industry collaborations. Countries like Germany, the UK, and France are investing in synthetic biology to strengthen healthcare innovation, while also expanding applications in environmental and food biotechnology. The region's emphasis on high-precision tools and stringent quality controls supports the adoption of synthetic gene solutions for vaccine development, rare disease research, and biopharmaceutical production. Additionally, Europe's growing startup ecosystem is contributing to a competitive and innovation-driven market landscape.
Key Insights
- The gene synthesis market is experiencing strong momentum due to rising demand from pharmaceutical and biotechnology companies aiming to streamline drug discovery and development using custom DNA constructs tailored for therapeutic targets.
- Increased utilization of gene synthesis in synthetic biology projects, particularly in designing biosynthetic pathways for the production of biofuels, enzymes, and chemicals, is significantly broadening the application landscape.
- Academic and research institutions are increasingly employing synthetic genes in genomics and functional biology studies, driving demand for cost-effective, high-fidelity gene synthesis solutions.
- Automation and AI-based sequence optimization tools are enhancing gene synthesis efficiency by reducing design errors, increasing synthesis throughput, and minimizing turnaround times in research workflows.
- The expansion of CRISPR gene editing technologies has escalated the need for precisely synthesized guide RNAs and donor templates, positioning gene synthesis as a key enabling technology in genome engineering.
- Growth in personalized medicine and precision oncology is fueling demand for customized gene panels and synthetic constructs for diagnostic assay development and therapeutic applications.
- Companies are investing in cloud-based platforms for gene sequence ordering and tracking, improving customer engagement and providing streamlined access to gene synthesis services across geographies.
- Asia Pacific is emerging as a high-growth region with increasing investments in life sciences, expansion of biotech start-ups, and favorable government initiatives promoting genomics research and bio-manufacturing.
- Concerns related to biosecurity, ethical considerations, and potential dual-use applications of synthetic genes are prompting regulatory bodies to establish stricter compliance and traceability frameworks.
- Strategic partnerships between gene synthesis providers and pharmaceutical companies are enhancing capabilities in vaccine development, therapeutic protein production, and monoclonal antibody engineering.
Market Scope
| Parameter | Detail |
|---|---|
| Base Year | 2024 |
| Estimated Year | 2025 |
| Forecast Period | 2026-2034 |
| Market Size-Units | USD billion |
| Market Splits Covered | By Method , By Service , By Application , By End-User |
| Countries Covered | North America (USA, Canada, Mexico) Europe (Germany, UK, France, Spain, Italy, Rest of Europe) Asia-Pacific (China, India, Japan, Australia, Rest of APAC) The Middle East and Africa (Middle East, Africa) South and Central America (Brazil, Argentina, Rest of SCA) |
| Analysis Covered | Latest Trends, Driving Factors, Challenges, Supply-Chain Analysis, Competitive Landscape, Company Strategies |
| Customization | 10 % free customization (up to 10 analyst hours) to modify segments, geographies, and companies analyzed |
| Post-Sale Support | 4 analyst hours, available up to 4 weeks |
| Delivery Format | The Latest Updated PDF and Excel Datafile |
Gene Synthesis Market Segmentation
By Method
- Solid-Phase Synthesis
- Chip-Based Synthesis
- PR-Based Enzyme Synthesis
By Service
- Antibody DNA Synthesis
- Viral DNA Synthesis
- Other Services
By Application
- Gene And Cell Therapy Development
- Vaccine Development
- Disease Diagnosis
- Other Applications
By End-User
- Biotechnology And Pharmaceutical Companies
- Academic And Government Research Institutes
- Contract Research Organizations
By Geography
- North America (USA, Canada, Mexico)
- Europe (Germany, UK, France, Spain, Italy, Rest of Europe)
- Asia-Pacific (China, India, Japan, Australia, Vietnam, Rest of APAC)
- The Middle East and Africa (Middle East, Africa)
- South and Central America (Brazil, Argentina, Rest of SCA)
Key Companies Covered
GenScript Biotech Corporation, Eurofins Scientific, Thermo Fisher Scientific Inc., Merck KGaA, Azenta Life Sciences (GeneWiz), Integrated DNA Technologies Inc. (IDT), Twist Bioscience Corp., Boster Biological Technology, ProMab Biotechnologies Inc., Biomatik Corporation, ProteoGenix Inc., OriGene Technologies Inc., ATUM, BioCat GmbH,Recent Developments
- June 2025 – Telesis Bio signed a licensing deal with Regeneron to integrate its Gibson SOLA™ platform into Regeneron’s R&D operations. This move is expected to accelerate on-demand gene synthesis and support advanced biologics development workflows.
- May 2025 – Integrated DNA Technologies (IDT) launched a collaboration with Elegen to provide ENFINIA™ Plasmid DNA, enabling rapid synthesis of NGS-verified long DNA fragments, streamlining gene therapy and vaccine development efforts.
- June 2025 – The North American gene synthesis market experienced notable growth with increased demand in synthetic biology, supported by advancements in CRISPR technology and personalized diagnostics across biotech hubs in the U.S.
- June 2024 – GenScript introduced the FLASH Gene service, offering ultra-fast gene synthesis with plasmid delivery within four business days, aiming to improve development speed in antibody and vaccine research programs.
- November 2023 – Twist Bioscience rolled out its Express Genes rapid synthesis service with delivery times as short as 5 to 7 business days, leveraging its proprietary silicon-based manufacturing platform to meet growing demand.
- January 2024 – GenScript completed the acquisition of CustomArray, enhancing its synthetic biology portfolio with high-throughput oligo synthesis capabilities to better serve CRISPR and targeted sequencing markets.
- October 2023 – Eurofins Genomics expanded its gene synthesis production capacity in Europe, aiming to reduce turnaround time for synthetic genes and enhance services for academic and industrial clients across the region.
- September 2023 – BGI Group announced improvements to its DNA synthesis and assembly platform, focusing on long-length genes and complex sequences to support next-generation synthetic biology initiatives in Asia.
- August 2023 – Thermo Fisher Scientific enhanced its gene synthesis offerings by integrating AI-based optimization tools for codon usage and structure prediction, improving accuracy and delivery of synthetic genes.
- July 2023 – Evonetix raised strategic funding to accelerate commercialization of its desktop DNA synthesis platform, which uses thermally controlled synthesis for high-fidelity gene construction at laboratory scale.
What You Receive
• Global Gene Synthesis market size and growth projections (CAGR), 2024- 2034• Impact of recent changes in geopolitical, economic, and trade policies on the demand and supply chain of Gene Synthesis.
• Gene Synthesis market size, share, and outlook across 5 regions and 27 countries, 2025- 2034.
• Gene Synthesis market size, CAGR, and Market Share of key products, applications, and end-user verticals, 2025- 2034.
• Short and long-term Gene Synthesis market trends, drivers, restraints, and opportunities.
• Porter’s Five Forces analysis, Technological developments in the Gene Synthesis market, Gene Synthesis supply chain analysis.
• Gene Synthesis trade analysis, Gene Synthesis market price analysis, Gene Synthesis Value Chain Analysis.
• Profiles of 5 leading companies in the industry- overview, key strategies, financials, and products.
• Latest Gene Synthesis market news and developments.
The Gene Synthesis Market international scenario is well established in the report with separate chapters on North America Gene Synthesis Market, Europe Gene Synthesis Market, Asia-Pacific Gene Synthesis Market, Middle East and Africa Gene Synthesis Market, and South and Central America Gene Synthesis Markets. These sections further fragment the regional Gene Synthesis market by type, application, end-user, and country.
1.1 List of Tables
1.2 List of Figures
2. Gene Synthesis Market Latest Trends, Drivers and Challenges, 2024- 2034
2.1 Gene Synthesis Market Overview
2.2 Market Strategies of Leading Gene Synthesis Companies
2.3 Gene Synthesis Market Insights, 2024- 2034
2.3.1 Leading Gene Synthesis Types, 2024- 2034
2.3.2 Leading Gene Synthesis End-User industries, 2024- 2034
2.3.3 Fast-Growing countries for Gene Synthesis sales, 2024- 2034
2.4 Gene Synthesis Market Drivers and Restraints
2.4.1 Gene Synthesis Demand Drivers to 2034
2.4.2 Gene Synthesis Challenges to 2034
2.5 Gene Synthesis Market- Five Forces Analysis
2.5.1 Gene Synthesis Industry Attractiveness Index, 2024
2.5.2 Threat of New Entrants
2.5.3 Bargaining Power of Suppliers
2.5.4 Bargaining Power of Buyers
2.5.5 Intensity of Competitive Rivalry
2.5.6 Threat of Substitutes
3. Global Gene Synthesis Market Value, Market Share, and Forecast to 2034
3.1 Global Gene Synthesis Market Overview, 2024
3.2 Global Gene Synthesis Market Revenue and Forecast, 2024- 2034 (US$ billion)
3.3 Global Gene Synthesis Market Size and Share Outlook By Product, 2024- 2034
3.4 Global Gene Synthesis Market Size and Share Outlook By Application, 2024- 2034
3.5 Global Gene Synthesis Market Size and Share Outlook By End User, 2024- 2034
3.6 Global Gene Synthesis Market Size and Share Outlook By Technology, 2024- 2034
3.7 Global Gene Synthesis Market Size and Share Outlook by Region, 2024- 2034
4. Asia Pacific Gene Synthesis Market Value, Market Share and Forecast to 2034
4.1 Asia Pacific Gene Synthesis Market Overview, 2024
4.2 Asia Pacific Gene Synthesis Market Revenue and Forecast, 2024- 2034 (US$ billion)
4.3 Asia Pacific Gene Synthesis Market Size and Share Outlook By Product, 2024- 2034
4.4 Asia Pacific Gene Synthesis Market Size and Share Outlook By Application, 2024- 2034
4.5 Asia Pacific Gene Synthesis Market Size and Share Outlook By End User, 2024- 2034
4.6 Asia Pacific Gene Synthesis Market Size and Share Outlook By Technology, 2024- 2034
4.7 Asia Pacific Gene Synthesis Market Size and Share Outlook by Country, 2024- 2034
5. Europe Gene Synthesis Market Value, Market Share, and Forecast to 2034
5.1 Europe Gene Synthesis Market Overview, 2024
5.2 Europe Gene Synthesis Market Revenue and Forecast, 2024- 2034 (US$ billion)
5.3 Europe Gene Synthesis Market Size and Share Outlook By Product, 2024- 2034
5.4 Europe Gene Synthesis Market Size and Share Outlook By Application, 2024- 2034
5.5 Europe Gene Synthesis Market Size and Share Outlook By End User, 2024- 2034
5.6 Europe Gene Synthesis Market Size and Share Outlook By Technology, 2024- 2034
5.7 Europe Gene Synthesis Market Size and Share Outlook by Country, 2024- 2034
6. North America Gene Synthesis Market Value, Market Share and Forecast to 2034
6.1 North America Gene Synthesis Market Overview, 2024
6.2 North America Gene Synthesis Market Revenue and Forecast, 2024- 2034 (US$ billion)
6.3 North America Gene Synthesis Market Size and Share Outlook By Product, 2024- 2034
6.4 North America Gene Synthesis Market Size and Share Outlook By Application, 2024- 2034
6.5 North America Gene Synthesis Market Size and Share Outlook By End User, 2024- 2034
6.6 North America Gene Synthesis Market Size and Share Outlook By Technology, 2024- 2034
6.7 North America Gene Synthesis Market Size and Share Outlook by Country, 2024- 2034
7. South and Central America Gene Synthesis Market Value, Market Share and Forecast to 2034
7.1 South and Central America Gene Synthesis Market Overview, 2024
7.2 South and Central America Gene Synthesis Market Revenue and Forecast, 2024- 2034 (US$ billion)
7.3 South and Central America Gene Synthesis Market Size and Share Outlook By Product, 2024- 2034
7.4 South and Central America Gene Synthesis Market Size and Share Outlook By Application, 2024- 2034
7.5 South and Central America Gene Synthesis Market Size and Share Outlook By End User, 2024- 2034
7.6 South and Central America Gene Synthesis Market Size and Share Outlook By Technology, 2024- 2034
7.7 South and Central America Gene Synthesis Market Size and Share Outlook by Country, 2024- 2034
8. Middle East Africa Gene Synthesis Market Value, Market Share and Forecast to 2034
8.1 Middle East Africa Gene Synthesis Market Overview, 2024
8.2 Middle East and Africa Gene Synthesis Market Revenue and Forecast, 2024- 2034 (US$ billion)
8.3 Middle East Africa Gene Synthesis Market Size and Share Outlook By Product, 2024- 2034
8.4 Middle East Africa Gene Synthesis Market Size and Share Outlook By Application, 2024- 2034
8.5 Middle East Africa Gene Synthesis Market Size and Share Outlook By End User, 2024- 2034
8.6 Middle East Africa Gene Synthesis Market Size and Share Outlook By Technology, 2024- 2034
8.7 Middle East Africa Gene Synthesis Market Size and Share Outlook by Country, 2024- 2034
9. Gene Synthesis Market Structure
9.1 Key Players
9.2 Gene Synthesis Companies - Key Strategies and Financial Analysis
9.2.1 Snapshot
9.2.3 Business Description
9.2.4 Products and Services
9.2.5 Financial Analysis
10. Gene Synthesis Industry Recent Developments
11 Appendix
11.1 Publisher Expertise
11.2 Research Methodology
11.3 Annual Subscription Plans
11.4 Contact Information
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FAQ's
The Global Gene Synthesis Market is estimated to generate USD 4.73 billion in revenue in 2025.
The Global Gene Synthesis Market is expected to grow at a Compound Annual Growth Rate (CAGR) of 16.68% during the forecast period from 2025 to 2034.
The Gene Synthesis Market is estimated to reach USD 18.95 billion by 2034.
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